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The impact of mindfulness on cancer-related cognitive impairment in breast cancer survivors with cognitive complaints
Melis,Michelle Schroyen,Gwen Leenaerts,Nicolas Smeets,Ann Sunaert,Stefan Van der Gucht,Katleen Deprez,Sabine
Melis,Michelle
Schroyen,Gwen
Leenaerts,Nicolas
Smeets,Ann
Sunaert,Stefan
Van der Gucht,Katleen
Deprez,Sabine
Abstract
Background Interventions that target cancer-related cognitive impairment (CRCI) to improve the quality of life of cancer survivors are needed. In this study, the potential of a mindfulness-based intervention to reduce CRCI in breast cancer survivors, compared with physical training and a wait list control group, was investigated. Methods Breast cancer survivors with cognitive complaints (N = 117) were randomly allocated to a mindfulness (n = 43), physical training (n = 36), or wait list control condition (n = 38). Participants completed neuropsychological tests and questionnaires before the intervention, immediately after, and 3 months after intervention. The primary outcome measure was the change in cognitive complaints over time. Secondary outcomes were objective cognitive impairment and psychological well-being. All outcomes were compared between groups over time using linear mixed models, including participants with missing values. Results Of the 117 included participants, 96 completed the three assessments. Participants in the three groups reported decreased cognitive complaints after intervention, without group differences. There were no between-group differences in objective cognitive impairment after intervention compared with baseline. Compared with the wait list control group, participants reported increased mindfulness skills and reduced emotional distress after mindfulness and reduced emotional distress and fatigue after physical training. Conclusion Contrary to the hypothesis, all groups reported an improvement in cognitive complaints over time. It is suggested that priming and acknowledgment of CRCI might alter the experience of cognitive impairment. Additionally, both mindfulness-based intervention and physical training can improve psychological well-being of breast cancer survivors with cognitive complaints.
Description
Date
2023
Journal Title
Journal ISSN
Volume Title
Publisher
Research Projects
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Journal Issue
Keywords
Breast Neoplasms/complications, Cancer Survivors/psychology, Cognition, Cognitive Dysfunction/etiology, Female, Humans, Mindfulness, Quality of Life, SDG 3 - Good Health and Well-being
Citation
Melis, M, Schroyen, G, Leenaerts, N, Smeets, A, Sunaert, S, Van der Gucht, K & Deprez, S 2023, 'The impact of mindfulness on cancer-related cognitive impairment in breast cancer survivors with cognitive complaints', Cancer, vol. 129, no. 7, pp. 1105-1116. https://doi.org/10.1002/cncr.34640
License
info:eu-repo/semantics/openAccess