Item

Declining antibody levels after hepatitis B vaccination in Down syndrome: A need for booster vaccination?

Eijsvoogel,N.B.
; 
Hollegien,M.I.
; 
Bok,L.A.
; 
Derksen-Lubsen,A.
; 
Dikken,F.
; 
Leenders,A.C.A.P.
; 
Pijning,A.
; 
Post,E.
; 
Wojciechowski,M.
; 
Hilbink,M.
... show 1 more
Abstract
We determined the anti-HBs titer in 227 children of all ages with Down syndrome (DS). Only 48.1% (95%CI: 35.1-61.3) of the DS children aged 7-10 years and 31.9% (95%CI: 22.1-43.6) of the DS children aged >10 years had a protective anti-HBs titer (≥10 IU/L). The geometric mean anti-HBs titer was significantly lower in the DS children; this suggests booster vaccination for HBV may be needed.
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Date
2017
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Tilburg University Research Output Collection
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SDG 3 - Good Health and Well-being
Citation
Eijsvoogel, N B, Hollegien, M I, Bok, L A, Derksen-Lubsen, A, Dikken, F, Leenders, A C A P, Pijning, A, Post, E, Wojciechowski, M, Hilbink, M & de Vries, E 2017, 'Declining antibody levels after hepatitis B vaccination in Down syndrome : A need for booster vaccination?', Journal of Medical Virology, vol. 89, no. 9, pp. 1682-1685. https://doi.org/10.1002/jmv.24813
URI
https://hdl.handle.net/20.500.14602/68628
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