Serum cholesterol decline and depression in the postpartum period
van Dam,R M Schuit,A.J. Schouten,E G Vader,H L Pop,V.J.
van Dam,R M
Schuit,A.J.
Schouten,E G
Vader,H L
Pop,V.J.
Abstract
We examined the relation between total serum cholesterol decline and depression in the postpartum period in a prospective study of 266 Dutch women, who were followed until 34 weeks after delivery. The decline in serum cholesterol between week 32 of pregnancy and week 10 postpartum was similar for women who became depressed (n = 63) in the subsequent period and women who did not (difference, 0.10 mmol/l; 95% confidence interval [CI] -0.16 to 0.37). Adjusting for age, multiparity, education level, smoking status, concurrent illness, and social support, the odds ratio of depression was 1.4 (95% CI, 0.64 to 2.9) for women in the highest tertile of serum cholesterol decline and 0.61 (95% CI, 0.28 to 1.3) for women in the intermediate tertile, as compared with women in the lowest tertile. Our results do not support the hypothesis that rapid serum cholesterol decline increases risk of depression in the postpartum period.
Description
Date
1999-04
Journal Title
Journal ISSN
Volume Title
Publisher
Research Projects
Organizational Units
Journal Issue
Keywords
Adult, Breast Feeding, Cholesterol, Depression, Postpartum, Female, Humans, Longitudinal Studies, Odds Ratio, Postpartum Period, Pregnancy, Prospective Studies, Risk Assessment, Social Support, Clinical Trial, Comparative Study, Journal Article, Research Support, Non-U.S. Gov't
Citation
van Dam, R M, Schuit, A J, Schouten, E G, Vader, H L & Pop, V J 1999, 'Serum cholesterol decline and depression in the postpartum period', Journal of Psychosomatic Research, vol. 46, no. 4, pp. 385-390. https://doi.org/10.1016/S0022-3999(98)00100-7