Impact of risk-dependent interventions on low haemoglobin deferral rates in whole blood donors
Baart,A Mireille van den Hurk,Katja de Kort,Wim L A M Huis In 't Veld,Elisabeth M J
Baart,A Mireille
van den Hurk,Katja
de Kort,Wim L A M
Huis In 't Veld,Elisabeth M J
Abstract
BACKGROUND: Blood donors with a relatively low haemoglobin (Hb) level at their previous donation attempt have an increased risk of Hb deferral at the subsequent donation attempt. The aim of this study was to investigate whether the interventions prolongation of donation interval and/or a dietary advice decrease the Hb deferral rate. METHODS: 11 897 whole blood donors with Hb levels from below to 0·2 mmol/l above the cut-off level for donation received either no intervention, a prolongation of the donation interval to six or twelve months, a dietary advice, or both. Deferral rates for low Hb levels at the subsequent donation attempt were compared in the different intervention groups. Additionally, the effects of the interventions on Hb deferral risk and donor return for a subsequent donation attempt were analysed using generalized estimating equations. RESULTS: The Hb deferral rate was substantially lower in the group that received a prolongation of the donation interval to six months than in the Control Group (12·9% vs. 6·3% in men and 20·4% vs. 13·4% in women). However, the additional benefit of twelve over 6-month interval prolongation was small, and no benefit of a dietary advice showed up. On the other hand, receiving a dietary advice increased the likelihood of donor return for a subsequent donation attempt. CONCLUSION: Implementation of a protocol for the prolongation of donation intervals to six months for donors with Hb levels from below to slightly above the cut-off level for donation may reduce the deferral rate for low Hb levels while keeping donor lapse at a minimum.
Description
Funding Information: The authors gratefully thank Michiel Balvers and Jeanne de Vries (Wageningen University & Research, Wageningen, the Netherlands) and Inez Jans (Gelderse Vallei Hospital, Ede, the Netherlands) for the development of the dietary advice. This study was supported by a Product and Process Development grant from the Sanquin Blood Supply Foundation; number: PPOC‐13‐002 / Lnr: 1878. Publisher Copyright: © 2020 International Society of Blood Transfusion Copyright: Copyright 2020 Elsevier B.V., All rights reserved.
Date
2020-04
Journal Title
Journal ISSN
Volume Title
Publisher
Research Projects
Organizational Units
Journal Issue
Keywords
DEFICIENCY, DONATION, Hb deferral, IRON SUPPLEMENTATION, PREDICTION, STORES, dietary advice, donation interval, haemoglobin, intervention, whole blood donors
Citation
Baart, A M, van den Hurk, K, de Kort, W L A M & Huis In 't Veld, E M J 2020, 'Impact of risk-dependent interventions on low haemoglobin deferral rates in whole blood donors', Vox Sanguinis, vol. 115, no. 3, pp. 171-181. https://doi.org/10.1111/vox.12885
License
info:eu-repo/semantics/closedAccess