Vitamin D status and health-related quality of life in patients with Type 2 diabetes
Krul-Poel ,Y.H. Westra,S. Wijland,H.J. Stam,F. Lips,P. Pouwer,F. Speight,J. Simsek,S.
Krul-Poel ,Y.H.
Westra,S.
Wijland,H.J.
Stam,F.
Lips,P.
Pouwer,F.
Speight,J.
Simsek,S.
Abstract
Aims To test whether vitamin D status was associated with health-related quality of life in people with Type 2 diabetes mellitus. Methods Demographic and clinical characteristics, including health-related quality of life scores, were obtained from 241 adult patients with Type 2 diabetes managed with oral hypoglycaemic agents. Health-related quality of life was assessed using the Short-Form 36 Health Survey. Multiple logistic regression analysis was used to investigate the association between vitamin D status and health-related quality of life, with adjustment for confounders. Results The mean age of the patients included in the study was 67 ± 8 years. Their mean HbA1c concentration was 52 ± 8 mmol/mol (6.9 ± 0.7%) and their mean serum 25-hydroxyvitamin D concentration was 59 ± 23 nmol/l. Vitamin D deficiency (serum 25-hydroxyvitamin D < 50 nmol/l) was present in 38% of patients. No significant associations were found between vitamin D status and health-related quality of life. Conclusions Vitamin D status was not associated with health-related quality of life in patients with Type 2 diabetes. This could be explained by the relatively high serum 25-hydroxyvitamin D concentration, good glycaemic control and relatively good health-related quality of life of all patients. A prospective study among patients with vitamin D deficiency and poor glycaemic control would be interesting for future research.
Description
Date
2016
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Publisher
Research Projects
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Keywords
SDG 3 - Good Health and Well-being
Citation
Krul-Poel , Y H, Westra, S, Wijland, H J, Stam, F, Lips, P, Pouwer, F, Speight, J & Simsek, S 2016, 'Vitamin D status and health-related quality of life in patients with Type 2 diabetes', Diabetic Medicine: Journal of the British Diabetic Association, vol. 33, no. 3, pp. 300–306. https://doi.org/10.1111/dme.12834