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Patient-reported outcomes following total thyroidectomy and lobectomy in thyroid cancer survivors: An analysis of the profiles registry data
van Gerwen,M. Cooke,P.V. Alpert,N. Mols,F. Genden,E. Schwartz,R.M.
van Gerwen,M.
Cooke,P.V.
Alpert,N.
Mols,F.
Genden,E.
Schwartz,R.M.
Abstract
Purpose Patient-reported outcomes are important in the surgical decision-making process for low-risk, differentiated thyroid cancer. Current study aimed to assess patient-reported outcomes in thyroid cancer survivors comparing total thyroidectomy (TT) and lobectomy (LT) using the Patient Reported Outcomes Following Initial treatment and Long term Evaluation of Survivorship (PROFILES) registry. Methods European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) scales, illness perception questions, Beliefs about Medicines Questionnaire (BMQ) scales and questions about thyroid surgery–related medication use were compared between thyroid cancer patients who underwent TT versus LT using descriptive analyses. Results In total, 58 thyroid cancer patients who underwent TT or LT were included in this study. None of the EORTC QLQ-C30 scales or questions regarding illness perception were significantly different between the surgical groups. Patients in the TT group had significantly higher belief in the necessity of their medication (21.0 vs 15.4; p = 0.003) and greater concerns about taking their medicines (14.7 vs 11.1; p = 0.008) versus patients in the LT group. Conclusion Concerns about post-surgical medication use specifically in the TT group may indicate that clinicians should consider LT in patients with low-risk, differentiated thyroid cancer when LT and TT are viable surgical options. Clinicians should be aware of the impact of post-surgical medication use in particular following TT and use this knowledge to align goals of treatment with the extent of surgery, allowing for a better-informed decision-making process.
Description
Date
2022
Journal Title
Journal ISSN
Volume Title
Publisher
Research Projects
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Journal Issue
Keywords
Beliefs, CARCINOMA, EXTENT, Perceptions, QUALITY-OF-LIFE, Quality of life, SURGERY, Surgery, Thyroid cancer, SDG 3 - Good Health and Well-being
Citation
van Gerwen, M, Cooke, P V, Alpert, N, Mols, F, Genden, E & Schwartz, R M 2022, 'Patient-reported outcomes following total thyroidectomy and lobectomy in thyroid cancer survivors : An analysis of the profiles registry data', Supportive Care in Cancer, vol. 30, pp. 687-693. https://doi.org/10.1007/s00520-021-06355-x