Personalized eHealth program for life-style change: Results from the "do Cardiac health advanced new generated ecosystem (Do CHANGE 2)" randomized controlled trial
Broers,Eva R. Widdershoven,Jos Denollet,Johan Lodder,Paul Kop,Willem J. Wetzels,Mart Ayoola,Idowu Piera-Jimenez,Jordi Habibovic,Mirela Do CHANGE Consortium
Broers,Eva R.
Widdershoven,Jos
Denollet,Johan
Lodder,Paul
Kop,Willem J.
Wetzels,Mart
Ayoola,Idowu
Piera-Jimenez,Jordi
Habibovic,Mirela
Do CHANGE Consortium
Abstract
Objective Unhealthy life-style factors have adverse outcomes in cardiac patients. However, only a minority of patients succeed to change unhealthy habits. Personalization of interventions may result in critical improvements. The current randomized controlled trial provides a proof of concept of the personalized Do Cardiac Health Advanced New Generation Ecosystem (Do CHANGE) 2 intervention and evaluates effects on a) life-style and b) quality of life over time. Methods Cardiac patients (n = 150; mean age = 61.97 +/- 11.61 years; 28.7% women; heart failure, n = 33; coronary artery disease, n = 50; hypertension, n = 67) recruited from Spain and the Netherlands were randomized to either the "Do CHANGE 2" or "care as usual" group. The Do CHANGE 2 group received ambulatory health-behavior assessment technologies for 6 months combined with a 3-month behavioral intervention program. Linear mixed-model analysis was used to evaluate the intervention effects, and latent class analysis was used for secondary subgroup analysis. Results Linear mixed-model analysis showed significant intervention effects for life-style behavior (F-interaction(2,138.5) = 5.97, p = .003), with improvement of life-style behavior in the intervention group. For quality of life, no significant main effect (F(1,138.18) = .58, p = .447) or interaction effect (F(2,133.1) = 0.41, p = .67) was found. Secondary latent class analysis revealed different subgroups of patients per outcome measure. The intervention was experienced as useful and feasible. Conclusions The personalized eHealth intervention resulted in significant improvements in life-style. Cardiac patients and health care providers were also willing to engage in this personalized digital behavioral intervention program. Incorporating eHealth life-style programs as part of secondary prevention would be particularly useful when taking into account which patients are most likely to benefit. Trial registration: https//clinicaltrials.gov/ct2/show/NCT03178305
Description
Funding Information: Source of Funding and Conflicts of Interest: The current study is funded by the European Commission’s Horizon 2020 program (grant number: 463735).
Date
2020
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Research Projects
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Keywords
cardiac health, life-style, behavior change, eHealth, DISEASE SELF-MANAGEMENT, CARDIOVASCULAR-DISEASE, HEART-DISEASE, WHOQOL-BREF, INTERVENTIONS, VALIDITY, PREVENTION, DEPRESSION, ANXIETY, SDG 3 - Good Health and Well-being
Citation
Broers, E R, Widdershoven, J, Denollet, J, Lodder, P, Kop, W J, Wetzels, M, Ayoola, I, Piera-Jimenez, J, Habibovic, M & Do CHANGE Consortium 2020, 'Personalized eHealth program for life-style change : Results from the "do Cardiac health advanced new generated ecosystem (Do CHANGE 2)" randomized controlled trial', Psychosomatic Medicine, vol. 82, no. 4, pp. 409-419. https://doi.org/10.1097/PSY.0000000000000802
License
info:eu-repo/semantics/closedAccess