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Age-related differences in the effect of psychological distress on mortality: Type D personality in younger versus older patients with cardiac arrhythmias

Denollet,J.
; 
Tekle,F.B.
; 
van der Voort,P.H.
; 
Alings,M.
; 
van den Broek,K.C.
Abstract
Background. Mixed findings in biobehavioral research on heart disease may partly be attributed to age-related differences in the prognostic value of psychological distress. This study sought to test the hypothesis that Type D (distressed) personality contributes to an increased mortality risk following implantable cardioverter defibrillator (ICD) treatment in younger patients but not in older patients. Methods. The Type D Scale (DS14) was used to assess general psychological distress in 455 younger (≤70 y, ) and 134 older (>70 y, ) ICD patients. End points were all-cause mortality and cardiac death after a median follow-up of 3.2 years. Results. Older patients had more advanced heart failure and a higher mortality rate ( %) than younger patients ( %), . Cardiac resynchronization therapy (CRT), but not Type D personality, was associated with increased mortality in older patients. Among younger patients, however, Type D personality was associated with an adjusted hazard ratio = 1.91 (95% CI 1.09–3.34) and 2.26 (95% CI 1.16–4.41) for all-cause and cardiac mortality; other predictors were increasing age, CRT, appropriate shocks, ACE-inhibitors, and smoking. Conclusion. Type D personality was independently associated with all-cause and cardiac mortality in younger ICD patients but not in older patients. Cardiovascular research needs to further explore age-related differences in psychosocial risk.
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open access
Date
2013
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Tilburg University Research Output Collection
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Keywords
SDG 3 - Good Health and Well-being
Citation
Denollet, J, Tekle, F B, van der Voort, P H, Alings, M & van den Broek, K C 2013, 'Age-related differences in the effect of psychological distress on mortality : Type D personality in younger versus older patients with cardiac arrhythmias', BioMed Research International, vol. 2013, 246035. https://doi.org/10.1155/2013/246035
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https://hdl.handle.net/20.500.14602/60498
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info:eu-repo/semantics/openAccess
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